Vietnamese Prime Minister Pham Minh Chinh sent a message of condolence to Secretary of State of the Vatican Cardinal Pietro Parolin. Deputy Prime Minister and Minister of Foreign Affairs Bui Thanh Son sent a message of condolence to the Vatican’s Secretary for Relations with States, Archbishop Paul Richard Gallagher.

US President Donald Trump and his predecessor Joe Biden led delegations to pay tribute to Pope Francis.

President Javier Milei of Argentina, Pope Francis's homeland, offered sincere praise and announced that Argentina will observe a seven-day national mourning period.

Brazilian President Luiz Inacio Lula da Silva decreed seven days of national mourning, and said humanity has lost a voice of respect and welcome for others.

Cuban Foreign Minister Bruno Rodriguez, Spain’s Minister of Justice, UK Prime Minister Keir Starmer, King Charles III, Italian Prime Minister Giorgia Meloni, leaders of Middle Eastern countries and Islamic organizations, and Ukrainian President Volodymyr Zelensky have all extended their condolences to the global Catholic community. They said Pope Francis was a courageous leader who never lost hope for a better world.

The Vatican has postponed a planned canonization ceremony for Carlo Acutis, known as the "saint of the digital age". Originally scheduled for this Sunday in St. Peter’s Square, the ceremony will be delayed to allow the Catholic Church to prepare for a funeral and begin the process of selecting a new Pope.

Carlo Acutis, an Italian teenager who died of leukemia in 2006 at the age of 15, was renowned for his deep devotion and use of technology to spread the faith. He is the first millennial to be considered for sainthood.